Microsoft Word 2010
The biggest change for experienced users is the introduction of ribbons rather than menu bars. Once you accept that fact you'll find that you can actually find features easier than before. In fact, you may assume that many features you find are new to Word 2010, where in fact, they probably existed before buried under a multitude of menu options.
For example, the following illustrates the choices available on the Home ribbon. Most of these features are not new but can now be easily accessed from this ribbon. The Home ribbon contains most features that you used to find on the Standard and Formatting toolbars.
All ribbon articles in HelpDesk Online are clickable (even this one). Just click on a button to learn more about that feature.
There are very few toolbars in Word 2010. You can, however, add buttons to your Quick Access bar.
If you're more than just a basic-features user, you'll probably want to take a look at the following articles sooner than later: